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it does not establish that reducing to 0.5 or 1.0 mg will hold the same plateau. One milligram has direct weight-loss evidence as an assigned treatment arm in type 2 diabetes, while small uncontrolled series suggest that dose reduction or reduced-frequency dosing can sometimes hold a plateau. No trial has established a Semaglutide step-down schedule

When someone stops taking GLP-1 injections against medical advice and experiences weight regain, they may lose insurance coverage for future prescriptions

Not injectable peptide

Diabetologia 60 , 531540 (2017)

For the scenario of "Currently Available Treatment," research data suggests Tirzepatide may be more relevant