The adaptor protein DDB1 (DNA damaging-binding protein 1) binds CULLIN4A/B-RBX1 complex and interacts with multiple WD40-repeat proteins (WDRs) to regulate cell cycle progression and DNA damage response 8
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When reduced glutathione performs this neutralization reaction with ROS, reduced glutathione itself becomes oxidized, which yields the oxidized form of glutathione known as GSSG
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