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Ello es as ya que la enzima que "reduce" el tripptido a partir de su forma oxidada, la glutatin reductasa, es constitutivamente activa e inducible en situaciones de estrs oxidativo

The binding of the respective ligands on these death receptors leads to the formation of a complex called the death-inducing signalling complex (DISC) (Mandal et al., 2020

Cullinan SB, Diehl JA

Integrating UGT inhibition data into the rule-of-two model significantly enhances the prediction accuracy for drug-induced liver injury (DILI) (119)