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Therefore, in order to contextualize the complexity of the metabolic network and the impact of Gclc on it, we analyzed our transcriptomic data using Compass, a flux balance analysis-based approach that allows the characterization and interpretation of metabolic diversity at the single cell level 70,71
The IGF-I and IGFBP-3 levels were measured via immunoradiometric assay using a DSL kit (Diagnostic Systems Laboratories, Webster, TX, USA)
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