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Block the receptor, eliminate the effect
Both engage central appetite circuits in the hypothalamus and hindbrain in research models, making them tools for probing satiety neurobiology and the durability of appetite suppression under sustained receptor activation
Do not use GLP-1 medications if you or your family have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
PVH, paraventricular hypothalamic nucleus
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