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Nature 399 , 7075 (1999)
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Controlling appetite is more important than fast changes on the scale
A systematic review and network meta-analysis found that GLP-1RAs, while reducing total weight and fat mass, led to a decrease in lean body mass (mean difference 0.86 kg), with the loss accounting for approximately 25% of the total weight loss [14]
Head-to-head comparison with aspirin While aspirin has been investigated for decades as a preventive therapy for colorectal cancer, its use has been limited due to adverse side effects such as an increased risk of bleeding
