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14 When the Wnt/-catenin signalling pathway is in the off-state, a -catenin destruction complex (DC) is formed in the cytoplasm, comprising AXIN, the APC protein, GSK-3, CK-1, and -catenin

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Translational Cancer Res, 2013;2(4)

Overall, this produces a net decrease in adipose tissue and a net energy consumption (i.e