Studies in aging-prone and cancer-prone rodent models highlight its relevance in the fields of gerontology and cancer biology 1,3,4
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[1] Common research areas include: NNMT blocking and NAD+ metabolism research Fat cell (adipocyte) growth and biology SIRT1 activation and gene-regulation studies One-carbon metabolism research Obesity, metabolic syndrome, and energy-balance models Muscle-mass and muscle-loss (sarcopenia) models How It Works 5-Amino-1MQ works by jamming the NNMT enzyme
Despite its importance, B12 deficiency is relatively common, especially among the elderly, vegans, and people with certain medical conditions