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The results showed that JYTLD improved renal function by inhibiting ROS production and regulating mitochondrial dynamics, alleviating renal tubulointerstitial fibrosis (TIF), and enhancing mitochondrial function

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Antimicrobial peptides, on the other hand, play a crucial role in the immune system, protecting the body against infections and diseases

Meanwhile, non-classical pyroptosis is also involved in TECs injury in DKD

Additionally, altered DSIP responses in major depression and suicidal patients suggest its role in addressing dysregulated stress in mood disorders (5)