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According to a 2019 review , GLP-1 and glucagon both play key roles in regulating thermogenesis and energy balance, suggesting that these hormones dont just influence appetite, but also how much heat your body produces at rest

"Some of the side effects we found, like nausea, are well known, and that shows that the method is picking up a real signal," says Sharath Chandra Guntuku, Research Associate Professor in Computer and Information Science (CIS) at Penn Engineering and the study's senior author

Development Stage One key difference is where each compound currently sits in the research timeline

Comparative Risk: In patients with Type 2 Diabetes, GLP-1 RA use was associated with a 7% lower cancer incidence compared with DPP4 inhibitors

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