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It binds to a GnRH receptor in the pituitary to increase the production of follicle-stimulating and luteinizing hormones, thereby stimulating the release of estrogen by the ovaries 116
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Clinical trials of semaglutide (another GLP-1 agonist) showed a temporary increase in diabetic retinopathy complications, particularly in patients with pre-existing retinopathy who experienced rapid glycemic improvement
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