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Mrtensson J, Meister A

Expression of the UDP-glucuronosyltransferase 1A locus in human colon

In other words, the lack of vitamin C biosynthesis allows our bodies to know more about our nutritional status and consequently set the proper baseline of HIF1 expression

This forces cancer cells to rely on exogenous serine uptake, which is preferentially channeled into sphingolipid biosynthesis to facilitate metastatic colonization ( 4.2.5 Melanoma In melanoma, the gene copy number of PHGDH is significantly increased

This creates a long-term deterrent that extends beyond the detection capabilities available at the time of collection