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References Kruse T, Hansen JL, Dahl K, Schffer L, Sensfuss U, et al

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+ = observed, - = not observed, A = EMA product information ( Human Human data was identified in the form of a case report on SGLT2 inhibitor use during pregnancy of a 31-year-old woman with type 2 diabetes on empagliflozin, metformin and insulin degludec who was found to be pregnant at the 5 th week of gestation ( GLP-1 agonists during lactation Animal The concentration of exenatide in the milk of mice was 2.5% of the maternal plasma concentration

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Circadian alignment