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Dihexa's preclinical design emphasized brain penetration, and animal studies showed CNS effects

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Harrison DJ et al

Our analysis extends to the specific metabolic adaptations inherent in various pathophysiological states, including metabolic shifts in neurodegenerative diseases (ND), heart metabolic reprogramming in cardiovascular diseases, disturbances in metabolic pathways in obesity and diabetes syndromes, autoimmune diseases, and cancer, focusing on how disease treatment can be achieved through targeting energy metabolism