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In vivo studies on urolithin A and spermidine Even though both UroA and spermidine can affect autophagy and mitophagy, in vivo studies with UroA predominantly focus on mitophagy, while those with spermidine focus more on autophagy
Furthermore, MPTP can be induced by bile acids, particularly glycochenodeoxycholate, which is one of the bile salts whose concentration rises by more than 20-fold during cholestasis (Yerushalmi et al., 2001)
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PMCID: PMC8995671
