| 6 min read GLP-1, a prominent gut hormone, is the target of many synthetic drugs on the market for the treatment of type 2 diabetes and obesity given its role in decreasing blood sugar levels and enhancing insulin secretion
To date, no studies have specifically investigated GLP-1RAs in early PsA
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The process of cellular senescence involves multiple factors, including DNA damage, telomere shortening, and epigenetic changes, which lead to cell cycle arrest and ultimately result in cellular senescence (Zhang et al., 2024)
GLP-1 agonists bind to the receptors in cells of the pancreas, improve their function by preservation, decrease apoptosis, and promote regeneration (2830)