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These findings establish ferroptosis as a key mechanism in myoglobin-induced nephrotoxicity ( Figure 5 )
The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis
Research has proposed that FOXO signaling may contribute to enhanced proteasomal and autophagy activity
Use of IHC can be helpful for diagnostic purposes and is common in human pathology where panels of immunohistochemical stains are used for supporting diagnoses
Kamboj A, Kiran R, Sandhir R (2006)
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