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Schematic depicting generation of Ttpa -liver specific knockout mice to evaluate depletion of -toc in driving tumour growth in mice
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In conclusion, we revealed novel structurefunction relationships of glutaredoxins, gained insights regarding the enzymatic conversion of glutathione- and non-glutathione disulfide substrates, and identified two distinct substrate interaction sites that include a scaffold residue and the conserved dual activator Lys105 in ScGrx7 and Lys26 in PfGrx
Shi H, Xu K, Huang M, Mao M, Ou J
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