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In addition, dichloroacetic acid (DCA), a pyruvate dehydrogenase activator, enhanced cardiac efficiency during IRI of isolated rat hearts by increasing glucose oxidation (59)
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Semaglutide is a GLP-1 receptor agonist, while tirzepatide combines GIP and GLP-1 receptor agonism, producing stronger effects on satiety and weight loss
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Body composition analyses have shown that both fat mass and lean mass decrease with weight loss, though fat mass accounts for the majority of weight lost
