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Despite the inability of erythrocytes to upregulate antioxidant enzymes at the transcriptional level, its antioxidant system, relying primarily on reduced glutathione (GSH), is involved in the regulation of the redox equilibrium in blood

In addition, people who have undergone gastrointestinal surgery may have a reduced ability to naturally absorb this vitamin from food

doi: 10.1203/00006450-200008000-00016 337 BeaumontABurtonARLemonJBennettBKLloydAVollmer-ConnaU

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