This interaction can occur by itself, but occurs at a much faster rate with the assistance of a group of enzymes call the Glutathione-S-Transferases (GST)(figure1) (5)
Fluoxetine administration to treat depression during pregnancy has been shown to induce greater changes in gene expression in the placenta of male infants than in that of female infants, emphasizing its sex-specific effects (Staal et al., 2024)
In the new structure, residues close to GSH are: A35, R38, L39, K42, R73, H76, L77, L80 from one subunit and R74, L77, N78, E81, Q127, N129, R130 from its neighbour
Cureus 12 , e11735 (2020)
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