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Although the exact mechanisms by which the coordinated actions of GLP-1 receptor agonism and NMDA receptor antagonism correct metabolic diseases await further elucidation, the extensive alterations in transcriptomic and proteomic responses within the hypothalamus, linked to glutamatergic signalling and synaptic plasticity, imply that the conjugate might elicit neurostructural changes in GLP-1-receptor-expressing neurons

Trauma-associated tinnitus: Audiological, demographic and clinical characteristics

Patients interested in participating should speak with their GP or specialist, who can advise on eligibility and refer to appropriate research centres

Epub 2022 Jun 14

Vitamin D supplementation in patients with cystic fibrosis: a systematic review and meta-analysis