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doi: 10.1016/j.ijbiomac.2024.129592 112 AmpemohottiTGolneshinAPillidgeCBrennanCHao VanTT
Phosphorylation of IGF-IR/InsR is elevated in ER+ breast cancer cells resistant to estrogen deprivation and tamoxifen, possibly due to increased secretion of IGF1/2 in these cells and elevated expression of retinoblastoma-binding protein 2 that inhibits IGFBP4/5 by interacting with ER-NRIP1-HDAC1 complex [107,108,109]
(2025) 14:e70105
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