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Dosage and application: Unless otherwise prescribed by the doctor, 1ml vitamin B12 1mg/ml twice a week is usually administered intramuscularly, but also slowly intravenously or subcutaneously at the beginning
The SURMOUNT-1 trial reported -22.5% weight reduction at the 15 mg weekly dose across 72 weeks (PMID 35658024)
Petersen JA, Wilm BJ, von Meyenburg J, Schubert M, Seifert B, Najafi Y, et al
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Macrophages switch between repair-promoting phenotypes and those that extend inflammation
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