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IECs turn over completely every three to five days, making them highly dependent on efficient growth factor signaling and adequate ECM scaffolding
Decreased CBF precedes the detectable changes of classical A and tau biomarkers, as well as brain atrophy, suggesting that reduced CBF could be a valuable biomarker in preclinical AD [138, 179]
doi: 10.3390/jcm9051306 47 JrgensenHFedorcsakPIsaacsonKTevonianEXiaoABesteMet al
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Achucarro, N
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