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Science 274:11331138
Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohns disease: a multi-omics Mendelian randomization study
GLP-1 medications appear to strengthen these connections
Both GLP-1 and GIP play a role in reducing appetite by stimulating neurons in the brains satiety center, and increasing insulin secretion in the pancreas
Genetic variants in GIPR and FTO, and MC4R may provide context for your baseline appetite regulation and GLP-1 pathway predisposition
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