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Laxative abuse: epidemiology, diagnosis and management

GLP-1 medications mimic it, activating receptors in the brain that control hunger and fullness

In a randomized control trial of two groups over 68 weeksone taking weekly semaglutide injections and the other receiving a placebothe group that received the drug lost 33.73 pounds on average, compared to 5.73 pounds in the placebo group

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Several randomised trials (STEP) [12,13,14,15] have compared outcomes following weekly subcutaneous administration of semaglutide to both placebo and lifestyle modification in patients mostly without diabetes with overweight/ obesity