In the MTX group, severe vacuolar degeneration and pyknotic nucleus in hepatocytes, increased number of activated Kupffer cells, inflammatory cell infiltration and marked sinusoidal dilatation and congestion were prominent features of the morphologic damage (Fig
Wu L, Zhou M, Li T, Dong N, Yi L, Zhang Q, et al
doi:10.1056/NEJMoa2502928 [2]1
Improved Insulin Sensitivity Can Change Hormone Balance Tirzepatide helps improve insulin sensitivity and supports better blood sugar regulation
Despite promising preliminary findings, these compounds are generally associated with a poor spatial and temporal control of the treatment as well as poor cancer selectivity, resulting in potential side effects and non-ideal drug doses