tirzepatide weight regain after stopping the withdrawal of (Zepbound) may wipe out many of the cardiometabolic gains made during weight loss, a post-hoc analysis of the SURMOUNT-4 trial indicated. Read more at: https://www.medpagetoday.com/endocrinology/obesity The role of Weight Loss

Clinical Points GLP-1 receptor agonists (GLP-1 RAs), such as exenatide, demonstrated efficacy in reducing heavy drinking days and total alcohol intake in individuals with obesity-related alcohol use disorders, suggesting a potential role for GLP-1 RAs in targeted treatments for alcohol dependency, particularly in patients with specific metabolic profiles

Loose skin risk correlates with amount of weight lost, speed of loss, age, and individual skin elasticity rather than the specific method of weight loss

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Both semaglutide and tirzepatide have been on the shortage list at various points, which has allowed compounding pharmacies to produce these medications legally