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typical therapeutic doses are well below the toxic threshold and are considered safe
Many people find the upper arm, abdomen and thigh to be the most comfortable and accessible
Likewise, during activity the mean decrease in pain score was 11.69 mm/h (95%CI 10.10-13.28 mm/h) for indomethacin and 11.38 mm/h (95%CI 9.98-12.79 mm/h) for prednisolone
a 2025 systematic review in orthopaedic sports medicine (Vasireddi et al., SAGE Journals) confirmed preclinical support but noted the absence of randomized controlled trials in humans
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