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Eli Lilly is targeting an FDA submission in late 2026
Once the timer goes off, the medication is ready for a comfortable, room-temperature injection
Databases searched include PubMed, Scopus, and Web of Science, focusing on articles published up to Feb 2026
GLP-1 medications are contraindicated for those with personal or family history of medullary thyroid cancer
According to NICE guidance , first-line therapy often includes corticosteroids (such as prednisolone or budesonide) for acute flares, alongside immunosuppressants like azathioprine, mercaptopurine, or methotrexate for maintenance
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