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Why It Pairs So Well With GLP-1 Agonists GLP-1 agonists like Retatrutide create a caloric deficit through multiple routes: appetite suppression, slowed gastric emptying, and (in Reta's case) glucagon receptor agonism that drives additional energy expenditure
Clinical studies (in both obesity and type 2 diabetes) consistently show that GLP-1 RA treatment leads to less hunger, increased satiety, and spontaneous decreases in daily caloric consumption (Zheng et al., 2024)
He was prescribed the drug for kidney disease and sleep apnea
Sethi NK, Mullin P, Torgovnick J, Capasso G
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