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Ann Indian Acad Neurol 11:179181
In women using HT, the most common adiposity-related diseases were hypertension (44%), followed by gastroesophageal reflux disease (38%) and dyslipidemia (25%)
Participants will receive weekly injections of either a GLP-1 or a placebo for 28 weeks
Key points: Leverage platform data from similar biologics Eliminate redundant toxicology studies Combine endpoints within the same study Use in vitro and computational models earlier Align with the 3Rs principle (Replacement, Reduction, Refinement) Important step toward more ethical and efficient ocular drug development
Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1)]
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