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First, the optimization of the Nrf2 pathway through targeted drug delivery, e.g., lipid nanoparticles (LPNs) loaded with sulforaphane or bardoxolone methyl could enhance endothelial uptake while avoiding systemic side effects (Zhang et al., 2024), and LNPs conjugated to VCAM-1 antibodies for inflamed vasculature targeting (Gu et al., 2025)
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It is found in every cell and is involved in more than 500 chemical reactions within our bodies
Monotherapy-versus-combination asymmetry
If Im being curious, as I want to be, I need to be open to listening and learning and actually looking at data
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