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Percentages were calculated using year-end reported financial results from Merck for 2021 and AbbVie for 2022
The dual-mechanism approach may also offer specific advantages for particular patient subgroups, including those with type 2 diabetes and obesity where cardiometabolic improvements beyond weight loss are clinically important
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Furthermore, fat mass exhibits even stronger associations with these bacterial genera, while fasting glucose levels correlate positively with Raoultella abundance, and insulin sensitivity indices correlate negatively with Atopobium and Scardovia
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