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Neutrophils are frequently detected in a highly active state in ARDS, which exacerbates lung injury and causes the release of pro-inflammatory cytokines

Carnitine palmitoyltransferase 1C The brain-specific carnitine palmitoyltransferase 1C (CPT1C) displays high-affinity to bind malonyl-CoA, but its enzymatic activity cannot be observed using conventional assays 43

Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

Beyond CPPs, other functional peptides have also been exploited for PNA delivery

The rationale behind this approach lies in the ability of ICD inducers to stimulate the spontaneous production of relevant antigens, DAMPs, and immune activation molecules within tumor cells