Research suggests combining both mechanisms produces additive or synergistic satiety effects beyond either pathway alone
It also supports your liver + boosts immunity + improves overall skin health
Pharmacological treatments applying neuromuscular blocking agents (NMBA), which can cause skeletal muscle relaxation by blocking the acetylcholine receptor neuromuscular junction, seem to be a possible solution for VILI (Naguib et al., 2002)
Hesperidin (Matias et al., 2017), rutin (El-Sayed el et al., 2008), and rhamno (Omar et al., 2017) can reduce the amount of free Ca 2+ located between brain cells when fighting against neurogenic excitotoxicity and can attenuate the decrease of the mitochondrial membrane potential and increase caspase-3 activity (Lutz et al., 2015)
24(8): 35765 Dolezal V, Tucek S