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In addition, tolerance can be overcome by increasing the dose, unlike tachyphylaxis
In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis
This means they must be converted to L-ascorbic acid before theyre of use to the skin
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