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Very effective for retinal inflammation (uveitis, macular edema) but significant side effects (cataract formation, pressure elevation, infection risk)

Based on clinical trials summarised in the European Medicines Agency's European Public Assessment Report (EPAR), gastrointestinal symptoms are among the most common adverse events during this period

National governments are responding by strengthening chronic disease management strategies and allocating higher healthcare budgets to address metabolic disorders

NO is an active molecule produced by the nitric oxide synthase (NOS) protein family, which directly binds and inactivates iron-containing enzymes [48] or reacts with superoxide anion radical O2 to form a highly active peroxy sulfoxide Nitrates (ooo-), which can attack membrane lipids and proteins of the pathogens, especially protein thiols [49]

Baron-Cohen S, Wheelwright S, Skinner R, Martin J, Clubley E