glp-1 versus glp-2 and Orchestrate Intestine Integrity, Gut Microbiota, and Immune System Crosstalk glp-1 vs glp 2 vs

Baseline patient characteristics, full frequencies of side effects and study structure are not described in detail

Trials included both, and the visceral-fat effect showed up in both

Use data to guide your benefits strategy Employers cant make informed decisions without the right data

Express Scripts defines medical necessity in its prior authorization criteria (the BMI thresholds, step therapy requirements, and comorbidity documentation described above)

In a separate study , published in JAMA in August 2025, the same researchers found that, across ages, GLP-1s were associated with lower risk of some obesity-related cancers, such as endometrial, ovarian, and meningioma cancers, but with an increased risk of kidney cancer, and nonsignificant changes for several other cancers