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Carnitine is required for the transport of long-chain acylcarnitines into the mitochondrial matrix, otherwise they accumulate in the mitochondrial intermembrane space and induce detrimental effects on both mitochondrial respiration and pyruvate metabolism
But personalized, physician-guided care will remain the cornerstone of effective obesity management
Primary Handling Editors: Liam Messin and Sonia Muliyil, in collaboration with the Nature Medicine team
or 2 kg)
Duarte S, Rosalen PL, Hayacibara MF, Cury JA, Bowen WH, Marquis RE, Rehder VL, Sartoratto A, Ikegaki M, Koo H
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