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Additionally, scientists examine its role in hypothalamic satiety signalling mechanisms
Related Reading Medication Glp 1 Can You Get Your Glp 1 Tested Maximus Glp 1 Found Glp 1 Medical and Editorial Standards Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims
Methods Construct modification and expression of full-length GLP-1R The optimized gene of full-length GLP-1R was cloned into the modified pFastbac1 vector at the BamHI/HindIII sites and the native signal sequence was replaced by haemagglutinin (HA) to enhance receptor expression (see primers in Supplementary Table 2), followed by a flag-tag, a 10 His-tag and a tobacco etch virus protease (TEV) site at the N-terminus
doi: 10.1016/j.molmed.2023.12.002 393 ReddyNDoyleMHanagandiPTaranathADahmoushHKrishnanPet al