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Insurers needed solutions that worked within the fiscal year, not across decades

2009 Feb;181(2):741-51. PMID: 19091331

Essentially, two groups can be distinguished: (i) molecules containing GSH or GSH-like moiety and (ii) molecules whose enzymatic activation occurs through a GSH-conjugate intermediate 109

those involving the -glutamyl portion of GSH, mediated by -glutamyl transpeptidases, with the rest involving the sulfhydryl moiety, which is responsible for the redox and nucleophilic reactions