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While glutathione is safe for most people, taking extremely high doses (over 2,000mg to 3,000mg daily) over a long period might lead to minor side effects like digestive upset or cramping

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The vasodilatory actions of NO play a prominent role in this process ( 2 O 2 ( Moreover, One mechanism through which RNS contributes to IBD pathology is the formation of Peroxynitrite(ONOO-), a highly reactive oxidant formed by the reaction of NO with O2 ( NaAAcT ) in rabbit intestinal villus cell brush border membrane during chronic intestinal inflammation