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Extended periods at elevated temperatures, however, accelerate peptide degradation through hydrolysis and oxidation reactions
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79 StefanoG
discovered that lactate, produced through glycolysis in pancreatic ductal adenocarcinoma (PDAC), can promote H3K18la under the catalysis of P300, thereby enhancing the transcription of mitotic checkpoint regulatory factors TTK and BUB1B
Furthermore, we adopted a two-way MR analysis process to more comprehensively explain the causal relationship between metabolites and SLE, as well as the mechanisms of the metabolic abnormalities associated with SLE onset and disease progression
