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In the dexamethasone-induced muscle atrophy model, exenatide had a significant anti-atrophy effect, and its core function is the activation of the Akt signaling pathway
PDE9 similarly lacks connection to dopaminergic circuits and has demonstrated only modest or heterogeneous cognitive effects in early clinical studies
Recent research and clinical trials have raised newer drugs like retatrutide to the top due to their potential to hit multiple pathways for appetite and glucose control
doi: 10.7150/ijbs.59965 27 ZhangXCaoCZhengFLiuCTianX
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