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Consequently, they provide measurable protection for both the heart and kidneys, even when glycemic targets are achieved

The demonstration of cardiorenal benefits with SGLT2i in clinical trials both for participants with CKD and type 2 diabetes and for those without [23,24,25] and the updated 2022 KDIGO guidelines recommending SGLT2i as first-line therapy for patients with CKD and type 2 diabetes regardless of glycemic control [6] have likely driven a shift toward their broader use for preventive cardiorenal protection and earlier implementation for patients with type 2 diabetes

Ask your healthcare provider if you fall into one of these groups

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Sethi et al., 2002)