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The choice of agent depends on individual patient factors, including treatment goals, tolerability, cost considerations, and patient preference
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These can keep you full for hours and push your next real meal out of reach, which is the opposite of what you want when total intake is already low
Attaching a fatty acid via a chemical linker to a specific residue on an already-assembled peptide requires controlling the proportion of conjugated versus unconjugated species, detecting and controlling free fatty acid or linker impurities, and monitoring for di- or poly-modification at unintended sites
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