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PLoS ONE 9 , e104771 (2014)
A sub-group analysis of non-diabetic patients was also performed
This imbalance is hypothesized to contribute to dysfunctions in the reward system, potentially manifesting as anhedonia and other depressive symptoms 45 , a clinical observation that aligns with the psychiatric side effects noted in GLP-1 RAs therapy
For researchers who have desensitized to dual agonist therapy, the addition of the glucagon receptor pathway provides genuinely novel stimulation
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