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Additionally, the body's inflammatory response to rapid weight loss or metabolic changes in the first few weeks can sometimes produce mild, transient fever-like sensations
Springer), 111147
(2025) Tirzepatide versus Semaglutide for Treatment of Obesity (SURMOUNT-5)
Shared side effects both medications can cause: Nausea (most common, especially when starting) Vomiting Diarrhea or constipation Stomach discomfort Loss of appetite Headache Dizziness Semaglutide-specific notes: Side effects are generally mild to moderate, and they often decrease as your body adjusts over the first few weeks
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